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emxisomeprole-femtor-activatedreceptor-gammaexpressioninhumanvascularsmoothmusclecells[J].Endocrimology.2001,142:3125-3134.[12]HsuchWA,JacksonS,LawBE.ControlofvascularcellproliferationandmigrationbyPPAR-gamma:anewapproachtothenlacrovasctdsrcomplicationofdiabetes[J].DiabetesCare,2001,24:392-397.[13]ItohH,DoiK.TanakaT.eta1.HypertensionandinsulinresJstsnee:roleofpemxisomeproleferator-aetivatedreceptor-~mma[J].ClinExpPharmaco1.1999,26:558-560.[14]MarxM,BoureierT,,~tkhovaGK,eta1.PPARgammaactivationinhumanendothelialcellsincremplasminogenactivatortypedexpression:PPART岫mmasapotentialmediatorinv8scIIl8rdisease[J】.ArteriosderThrombVaseB.ol,1999,19:546—551.[15]KatoK,SatohH.End0Y,ecco shoes outlet,eta1.Thiazolidinedionesdownregulateplasminogenactivatorinhibitortype-1expressioninhumanvascularendothelialcells:apossibleroleforPPAB~mm.ainendothelialfunction[J].BiochemBiophysResCommun.1999,258:431--435.[16]KageyamaH,HiranoT,OkedaK,mbt italia,eta1.LipoproteinlipasemRNAinwhiteadiposetissuebutnotinBkdet8lmuscleisincreasedbypioglitamnethroughPPAB-gamma[J].BiochemBiophysResConunu—n,ugg boots España,2003,3o5:22—27.[17]WangMH,WiseS.I七T,eta1.Toglitozone,supra shoes outlet,anantldiatetieagent,inhabitscholesterolbiosynthesisthroughamechanismindependentofperoxisomeproleferator-activatedreeeptor[J]J)iabetes,uggs kopen,1999,48:254-260.[18]PemhadsinghHA.Treatlngthemetabolicsyndromeusing8nnsilI地ccotorantagoniststhatsehetivdymodulatep时0a【i8omeproliforator-activatedreceptor--mmma[J].IntJBiochemCellBiol,2005.9:9-14.收稿日期:2007·l1-05●作者简介:夏昆(1968一),男.河北人,硕士学位,主治医师.主要从事心内科临床及冠脉介入治疗。
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