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 Wysłany: Pon 23:12, 28 Lut 2011 Temat postu: IL-5 in the physical model of allergic rhinitis na |
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IL-5 in the physical model of allergic rhinitis nasal mucosa and its significance
And so on. Kebimin rhinitis model in guinea pigs hypersensitive pathology light microscope electron microscope observation [J]. Beijing University of Traditional Chinese Medicine, 1999,22 (6) :36-38. [10] SehmiR,p90x calendar, WoodLJ, WatsonR. Allergu-inducedincreasesinIL-5receptoralpha-subunitexpressiononbonem ~ ITOW · derivexlCD34cellsfromasthmaticSUbjects [J]. JournalofClinicalInvestigation ,1997,120:2457-2466. [11] Yan Zhiqiang, Zhang as new. Progress in eosinophil function [J]. International Journal of Otolaryngology Volume, 2004,28 (5) :304-307. [12] Wang Xiang. IL-3, IL 5 and GM-CSF of a common B-chain receptor antisense oligonucleotide inhibits antigen stimulated eosinophilia syndrome and airway hyperresponsiveness [J]. International Journal of the volumes, 2003,30 (3) :132-133. fl3 Liu Yongqi, Wang. Nature of the immunological deficiency syndrome [J]. Journal of Traditional Chinese Medicine, 2003,supra shoes outlet,9 (5): 327.330. [14] Tang Yueying, students have Yi, Chen words, and so on. Allergic rhinitis and its relationship with TCM syndrome and interferon interleukin _4 one correlation [J]. Chinese Journal of Integrated Traditional and Western Medicine, 2007,tory burch shoes,15 (1) :9-11. Project Source: Shanghai Municipal Health Bureau in the subject of medical research funds (No. 2OO4L0O8C) Received :2009-07-06; Revised :2009-09.28 (Editor ceramic beads) Article ID :1001 -6910 (2009) 12 -0012-04 Magnolia essential oil of BALB / c mice through experimental study - sensitive airway inflammation Yang Jinhua, Li Yin Chao (1. First Affiliated Hospital of Traditional Chinese Medicine, Zhengzhou 450000; 2. Zhengzhou University College of Pharmacy Zhengzhou 450052, China) Abstract Objective: To investigate the essential oil of Magnolia BALB / e mice with allergic airway inflammation. Methods: The ovalbumin (OVA) sensitized with Freund's adjuvant induced BALB / c mice with asthma, their view of Cha Xinyi oil bronchoalveolar lavage fluid (BALF),supra for sale, white blood cell (WBC) count of the number and classification,asics australia, protein content, lung pathological changes of mucosal infiltration of the bronchioles and lung eosinophils (Eos) of the number. Results: Magnolia essential oils can significantly reduce the BALI ~ 'in the Eos number (P <0.05), protein content of lung tissue Eos (P <0.05) and other inflammatory cell infiltration, and the dose-effect relationship to the role of high-dose compared with Magnolia Oil strong. Conclusion: The Magnolia oil control effect of allergic asthma, possibly by inhibiting the inflammatory infiltration of lung tissue Eos achieved. Keywords: Magnolia oil / pharmacodynamics airway inflammation / drug effects in bronchoalveolar lavage fluid / pharmacodynamics in the ring eosinophils Key words: R562.25 literature flag code: B to the terms of the pathogenesis of bronchial asthma There are two successive phase of pathological response, the early asthmatic reaction (earlyasth.maticreaction, EAR) and late phase reaction (1ateasthmaticre-action, LAR) 1-2], EAR mainly by the degranulation of airway mast cells mediated by guide, LAR mainly by the infiltration of airway inflammatory Eos mediated. I pre-sensitized and challenged with OVA produced in asthmatic guinea pig asthma model characterized by EAR, initially confirmed Magnolia essential oil has a more significant role in inflammation control EAR. On the basis of this study further observed Magnolia essential oils to airway inflammation characterized by LAR BALB / c mouse model of airway inflammation in asthmatic effects, are reported below. 1 Materials and methods 1.1 Animal Health BALB / c mice of clean grade, 50 body mass (20 ± 2) g, male and female, by the Experimental Animal Center of Henan Province, animal production license number: SCXK ( Yu) 2005-0001. 1.2 Drugs and try Jing Magnolia essential oil from Hualong Lily Magnolia Development Co., Ltd. of Henan Province Nanzhao provided sealed brown bottle, 4 ℃ refrigerator, When you use the 0.5% Tween. 80 Magnolia preparation of oil 18L per ml of liquid, |
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