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 Wysłany: Czw 14:47, 24 Lut 2011 Temat postu: timberland scarpe Integrative Medicine on the trea |
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Integrative Medicine on the treatment of refractory reflux esophagitis in 40 cases
Cases; age of 2473 years old, average 47.4 years old. All cases were diagnosed by endoscopy reflux esophagitis, disease duration 3 months to 2 years; mild in 5 cases, in Moldova, and 9 down. Severe 6 down. After a day and night sternum, xiphoid lower and upper abdominal burning, salt being 24 cases, there is the sternum, the xiphoid lower and upper abdominal pain l6 cases and 8 cases of fullness; a night substernal pressure, congestion l9 sense of those cases, postprandial and nocturnal acid reflux or regurgitation of food to the mouth of those who ll cases of poor swallowing or swallowing pain in 5 cases. Have received ranitidine (or famotidine) and metoclopramide (or domperidone) 2 months to 1 year of regular treatment, but esophagitis symptoms persist or relapse. 1.2 The treatment of patients with severe symptoms, endoscopy esophagitis grade in moderate to severe, erosive ulcer pathology report, given omeprazole 2oT / times, 132 times each; mild patient for omeprazole 20mg, day 1. Treatment for 48 weeks. During this period, plus Chinese herb Sini (medicinal Bupleurum 12g, white peony root 15g, citrus aurantium 20g, licorice 5g.), Each 213 l agent. Even for 4 weeks. 1.3 determine the efficacy of standard markedly: reflux esophagitis symptoms completely disappeared, the performance of endoscopic esophagitis disappeared. Effective: symptoms of reflux esophagitis was significantly reduced, endoscopy showed mild esophagitis grade change. Invalid: After treatment, symptoms of reflux esophagitis and endoscopic grading of esophagitis did not change [1]. 2 Results 2.1 The effect of statistics in the 40 cases, 31 cases markedly effective, 7 cases, 2 cases, the total effective rate was 95%. 2.2 histopathological examination by the WM therapy treatment, histopathology was on active inflammation subsided or disappeared. Before treatment, pathology reports, 26 cases of esophageal mucosa with chronic inflammation,[link widoczny dla zalogowanych], erosion, 25 cases after treatment of chronic inflammation of esophageal mucosa, l there are still cases of erosion; erosion before treatment in 8 patients with ulcer after treatment for the chronic inflammation of esophageal mucosa ; 6 cases before treatment of chronic inflammation of the esophagus shed for cattle with squamous cell membrane hyperplasia, 4 patients after treatment of squamous epithelial hyperplasia disappeared. 3 Discussion 3.1 reflux esophagitis is due to lower esophageal sphincter dysfunction,[link widoczny dla zalogowanych], esophageal body clearance function to reduce, delay gastric emptying, gastric acid, pepsin and other gastric contents due to anti-shed mucosal inflammation in the esophagus. Clinical H2 receptor antagonistic accustomed to using agents such as ranitidine, famotidine, etc., and prokinetic drugs to treat the disease, Tam effective rate of 70% l2J. We use Chinese and Western medicine, Chinese Taiwan, Sini omeprazole treatment of the disease, to obtain a more satisfactory outcome, of which 3l cases markedly effective, 7 cases, 2 cases,[link widoczny dla zalogowanych], the total effective rate was 95%. The performance of endoscopic esophagitis and significantly improved abnormal esophageal pathology has improved significantly. 3,2 lower esophageal sphincter dysfunction and acid reflux disease reflux esophagitis key. Omeprazole inhibit gastric acid secretion and increase the role of the lower esophageal sphincter. Parietal cells in omeprazole effect on the small tube at the top of endocrine H. k. A1 = P enzyme (proton pump),[link widoczny dla zalogowanych], inhibiting gastric acid secretions in the final steps to the wall of H cells can not excrete almost completely inhibited the basic state and a variety of gastric acid secretion after stimulation. It is the role of the most powerful gastric acid inhibitors. Powerful acid-suppressing effect of omeprazole can increase gastric pH value to 4.0,[link widoczny dla zalogowanych], the sharp drop in the activity of pepsin, thereby reducing the esophageal inflammation; omeprazole strong acid suppression, the role of negative feedback caused by high hypertriglyceridemia and increased gastric secret cable tension of the lower esophageal sphincter, thereby reducing reflux. 3,3 Sini for the Chinese medicine classic (Treatise on) in the name of the party, with liver and gas Jieyu effect. Modern research shows that Sini can regulate gastrointestinal motility, promoting gastric motility and emptying 4. J. Our clinical observations show that Chinese and Western medicine therapy for refractory reflux esophagitis is effective, it is worth further study.
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