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 Wysłany: Czw 13:12, 10 Lut 2011 Temat postu: moncler outlet Polio immunization in 2006, Jiangsu |
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Polio immunization in 2006, Jiangsu Province, the level of monitoring and analysis
Anti-malaria medication is the key. The peak of diarrhea was 6 to 10 months, more than occurred in recent years, the city school children and outbreaks of dysentery in rural areas, so rural areas,[link widoczny dla zalogowanych], in schools and knowledge of missionary to further strengthen health and disease prevention, food hygiene management of drinking water, while medical agencies should also strengthen the monitoring and management of diarrheal disease, prevention of epidemic outbreaks. * Illness r: A-Taiwan polio immunization in 2006, Jiangsu Province, the level of monitoring and analysis Hu Ying, cold Hongying, Yan Xuling (Center for Disease Control and Prevention in Jiangsu Province, Nanjing 210009) Document code】】 R181 B CLC .38 Article ID】 1OO6-9O7O (2OO8) O1 ~ OO26 O2 Key words for a polio; immunization levels; monitoring made since 1988 to 2000 WHO global eradication of poliomyelitis (polio) target, the global eradication of Received date :2007 polio made -08-29 Author: Ying Hu (1979), female,[link widoczny dla zalogowanych], Liaoning Tieling, technicians. Yi Tang Ling fall on March 2,[link widoczny dla zalogowanych], No. 1 19 JiangsuJPreyMed, March, 2008, V01.19, N0.1 significant progress. Jiangsu Province for the history of high incidence of polio province, 1992 - 2000 carried out in the province for many years to strengthen immunity, annually, beginning in 2001 to carry out immunization in some areas, and each year since 1995, both in the province of the pumping points for the normal population levels of immunity and immune monitoring of the success rate to achieve the monitoring of existing populations, immune surveillance in 2006 is now reported as follows. 1 Materials and methods 1.1 monitoring object choice Huai'an, two monitoring points in Nantong City, polio antibody levels, monitoring of objects 0, 1 ~ 2,3 ~, 5 ~, 7 ~, 15 ~ 19,20 ~ 7-year-old age group of children. 1.2 Mining finger peripheral blood specimen collection 0.3ml, after separation of the serum - 20. C cryopreservation for inspection. 1.3 Detection Technology by the Ministry of Health management protocols polio immunization and antibody detection methods in the serum from 1:4 diluted 4 times to do a continuous, positive antibody titer ≥ 1:4, , the standard reference serum requirements polio I, II, III-type determination of serum titers of two or more stable. Antigens need to use SabinI, II, III-type strain prepared by a group of antigen (virus) and used in the experiment, the titer stabilized at 10. LogTCIDo / ml or more,[link widoczny dla zalogowanych], Hep-2 cells by the Chinese Center for Disease Control and Prevention National Polio Laboratory. 2 Results 2.1 The level of polio immunization serum samples were collected, 700 were eligible, of which 350 copies of the Huai'an and Nantong, the distribution of various types of GMT and the neutralizing antibody positive rate in Table 1. Table 1 Huai'an and Nantong cities of polio immunization level monitoring results 2.2 antibody levels in different age groups were sampled for each age group, 100 in different age groups, workers, Ⅱ, Ⅲ type of GMT are the highest 3-year-old group, to 15-year-old group was the lowest. Table 2, Figure 1. Table 2 different age groups to monitor the results of polio neutralizing antibody 01 ~ 21-45-67 ~ I4l5l920, aged f years) Figure 1 polio in different age groups and 3 discuss the monitoring of antibody distribution showed that the immune monitoring sites in Jiangsu ridge 2006 Gray 3 antibody positive rate of type 99 or more children between the monitoring points was no significant difference in antibody positive, GMT Nantong slightly higher than the Huai'an, different age groups polio type 3 antibody titers were 3 years old was the highest, lowest 15-year-old group, different age groups the level of polio antibody titers before the 3-year-old group increased with age, then decreased, a phenomenon in the age group 15 to the end of each year may be natural antibodies due to reduction. In 2O ~ increased after the age of the phenomenon appeared. 3 of the same age group, type of work between the GMT-type distribution is the highest, Ⅱ-type second, III-type minimum, which may be due to differences in polio vaccine itself causes. This year's test results be different from previous years, mainly grouped in this year's situation is different from previous years, changed the age distribution, the results of this year itself is relatively high, suggesting that children in Jiangsu Province, has become an effective immune barrier to successfully control and blocked the spread of wild poliovirus. Jiangsu Province is still in a critical stage of polio eradication,[link widoczny dla zalogowanych], with this selected population sample monitoring points can only represent the antibody level, another monitoring system needs further improvement, especially in the standard testing, differential diagnosis, reagents, supplies, personnel training and research in this regard should further increase the force to further consolidate the results of eradication of polio. Flail coral reef iv. I is a one by one】
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