veoexrmpzt
Dołączył: 21 Lut 2011
Posty: 371
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Skąd: England
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 Wysłany: Wto 8:30, 08 Mar 2011 Temat postu: mbt scarpe nmb abi euji inm |
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,[link widoczny dla zalogowanych]
Energy metabolism and Alzheimer's disease
TRPV5 is present in human and murine osteoclasts (osteoclast, OC) absorption surface microvilli brush border formation,[link widoczny dla zalogowanych], and bone resorption, and OC in the Oc ca osteoporosis (OP) are closely related. Therefore, further research TRPV5, clinical understanding of the pathogenesis of OP and its control is of great significance. a new type of Ca function, and bone metabolism in a very close relationship between Ca2 TRPV5 in the rabbit, rat, human and other species are present, and its protein sequence with a high degree of homology, some of the functional structure of area structures are identical. By Northern blotting, RT. PCR method and immunohistochemistry confirmed that TRPV5 protein present in a ca For the ca VanderEerden other cultured from bone marrow cells to the OC and inoculated into the tibial cortex in slices and found that the rules of the formation of resorption, inoculation TR. PV5 . OC volume increased and the increase in the number may be compensatory OC's functional limitations. with cellular immunity of the Fund: Ministry of Education Doctoral Foundation (20050183013) Biography: Che Ming Studies (1975 -), male, a Ph.D., attending physician division, mainly engaged in the research of osteoporosis. Learning methods to TRPV5 protein coloring found in the electron microscope, found in human and murine TRPV5 OC absorb the formation of surface microvilli brush border. So TRPV5 may Oc in bone resorption and Oc ca ion transport function in closely related. Prior to 1999, on the ca ca In 1999, the Netherlands, first reported by Hoenderop so smooth in Xenopus oocytes that a new transport channel protein and Ca2 relevant,[link widoczny dla zalogowanych], and by animal experiments, intestinal epithelial cells in the kidney and confirmed its existence. And confirmed that they and the ca wild-type (TRPV5) mice showed a relatively TRPV5 polyuria, and a lot of calcium excreted in the urine. Serum analysis showed that TRPV5 in mice to maintain a normal plasma ca Using micro-acupuncture of the renal unit found in the body ca concentration is very high ca mice, showing initiative reducing the absorption of calcium, vitamin D,[link widoczny dla zalogowanych], despite the increase in the amount of absorption of calcium and no improvement, and there was a high occurrence of hypercalcemia and hypercalciuria. In addition, the application of x-ray tomography Contrast TRPV5 and TRPV5 in mice of a femoral head, femoral shaft and found a small rotor, TRPV5 also showed a significant imbalance in bone structure (trabecular and cortical bone decreased significantly thinner). These show that the important function of TRPV5 is Active uptake and maintenance of ca ca Activated form of vitamin D, 1,[link widoczny dla zalogowanych],25 (OH): vitamin D3, on the ca normal primate marrow mononuclear cells, induced a large multinucleated cells. other vitamin D analogues (such as: parathyroid hormone, prostaglandin E:, calcitonin) could not induce the formation of multinucleated cells, and calcitonin
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