nyenaceyg
Dołączył: 13 Gru 2010
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Skąd: England
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 Wysłany: Czw 15:38, 03 Mar 2011 Temat postu: Intracranial hematoma after traumatic brain injury |
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,[link widoczny dla zalogowanych]
Intracranial hematoma after traumatic brain injury in cerebral infarction (16 cases)
Within 24 hours after treatment began,[link widoczny dla zalogowanych], asked defecation,[link widoczny dla zalogowanych], frequency,[link widoczny dla zalogowanych], nature,[link widoczny dla zalogowanych], or with symptoms and adverse reactions. Results: The difference between the two groups was significant (P <0.O1), better than oral mannitol salt catharsis cathartic. Conclusions: Oral mannitol salt catharsis cathartic method is better than oral satisfaction, resulting in short bowel when asked, the effect is reliable, and no obvious side effects and is worthy of promotion. Key words acute poisoning cathartic magnesium sulfate 20% mannitol or oral gastric tube after gastric lavage laxative into catharsis, to clear toxic substances into the intestine to reduce absorption of toxic, acute oral toxicity is to save an important therapy in patients with measures. Choose more effective and safe cathartic method, for improving the success rate has important clinical significance. From July 2002 to begin human hospital emergency department with acute oral poisoning 35 patients who applied method of oral mannitol cathartic effect clinical observation, received good results, are reported as follows: Method 1.1 Case 1 data and group selection in June 2002 ~ March 2003, by Random House of mouth of people who were 35 cases of acute poisoning in the observation group. From August 2001 ~ May 2002 randomly selected hospital cases of acute poisoning by mouth 30 cases as control group. Observation group, the average age was 28.6 years, were under the age of the control group was 29.5 years. No significant difference between the two groups. The second group of patients who were excluded contraindication catharsis. 1.2 Treatment methods using randomized controlled study. The observation group, 35 cases, gastric lavage within 30 minutes after the dispensing operation by the nurses, conscious of a one oral mannitol 20% 250ml, coma, restlessness, or do not match those 6 patients, and gastric lavage prior to extubation to the end 20% mannitol injection tube 250ml. Control group of 30 patients with gastric lavage 30 minutes after the oral or gastric tube into the 25 grams of magnesium sulfate (2 patients who coma from the stomach juice of 25 grams of sodium). 1.3 OUTCOME MEASURES observation group and control group were in the service or through a gastric tube into the El mannitol, or magnesium sulfate (or sodium) after 24 hours of observation by the physician to appear defecation time, frequency, nature or accompanying symptoms and side effects . 2 Results from the study group of oral mannitol bowel time to onset of 24 patients within 6 hours, 7 ~ l2-hour period in 6 cases, l3 ~ 24 hours in 5 cases, bowel movements within 24 hours of 1 to 3 times in 29 cases, 4 to 6 times were 6 cases. Would dilute water samples were not associated with side effects such as abdominal pain or tenesmus. El service from the control group, salts of laxatives defecation time to onset, 4 patients within 6 hours, 7 ~ l2 hours l2 cases, l3 ~ 24 hours, 6 cases of bowel movements within 24 hours of 1 to 3 times 2O cases, there is eight cases of bowel reaction does not appear. 2 cases of organophosphate poisoning the fourth day in the hospital died due to rebound. Significant difference between the two groups (P <0.01), El service is better than mannitol salt catharsis cathartic. 3 to discuss the clinical 20% of the commonly used hypertonic mannitol as dehydrating agent. Not be absorbed in the intestine after oral administration, is a cathartic permeability: its mechanism of El serving the drug, the use of the hyperosmolar theory, prevent the intestinal absorption of salt and water, is expanding gut, stimulate the intestinal wall, and promote intestinal peristalsis, resulting in permeability and volume of the cathartic effect, resulting in bowel movements, to clear the remnants of the small intestine, large intestine of toxins. This study showed that oral administration of oral mannitol salt catharsis cathartic method is more satisfactory, resulting in short bowel, the effect is reliable, and no obvious side effects, play an important role to improve the success rate. Experience of treatment are summarized as follows: (1) source of widespread drug mannitol, economical, convenient, good taste, easy to patients. (2) can be used for a variety of El service poisoning. Suppress the central nervous system without the worry of magnesium, salts of magnesium sulfate as a laxative and sometimes excessive intestinal absorption of magnesium ions, may produce central nervous system inhibition, it is in renal failure and coma disabled. Of toxic or corrosive catharsis when the patient is extremely weak taboo. When the poison has caused severe diarrhea, they do not have to catharsis. (3) saline or mineral water served at the same time El 1000 ~ 200Oral catharsis better. (4) and severe constipation in elderly persons with caution. (5) times more diarrhea, more than the amount appropriate according to the disease are advised to oral or intravenous rehydration.
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