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 Wysłany: Pon 23:12, 28 Lut 2011 Temat postu: IL-5 in the physical model of allergic rhinitis na |
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IL-5 in the physical model of allergic rhinitis nasal mucosa and its significance
And so on. Kebimin rhinitis model in guinea pigs hypersensitive pathology light microscope electron microscope observation [J]. Beijing University of Traditional Chinese Medicine, 1999,22 (6) :36-38. [10] SehmiR,[link widoczny dla zalogowanych], WoodLJ, WatsonR. Allergu-inducedincreasesinIL-5receptoralpha-subunitexpressiononbonem ~ ITOW · derivexlCD34cellsfromasthmaticSUbjects [J]. JournalofClinicalInvestigation ,1997,120:2457-2466. [11] Yan Zhiqiang, Zhang as new. Progress in eosinophil function [J]. International Journal of Otolaryngology Volume, 2004,28 (5) :304-307. [12] Wang Xiang. IL-3, IL 5 and GM-CSF of a common B-chain receptor antisense oligonucleotide inhibits antigen stimulated eosinophilia syndrome and airway hyperresponsiveness [J]. International Journal of the volumes, 2003,30 (3) :132-133. fl3 Liu Yongqi, Wang. Nature of the immunological deficiency syndrome [J]. Journal of Traditional Chinese Medicine, 2003,[link widoczny dla zalogowanych],9 (5): 327.330. [14] Tang Yueying, students have Yi, Chen words, and so on. Allergic rhinitis and its relationship with TCM syndrome and interferon interleukin _4 one correlation [J]. Chinese Journal of Integrated Traditional and Western Medicine, 2007,[link widoczny dla zalogowanych],15 (1) :9-11. Project Source: Shanghai Municipal Health Bureau in the subject of medical research funds (No. 2OO4L0O8C) Received :2009-07-06; Revised :2009-09.28 (Editor ceramic beads) Article ID :1001 -6910 (2009) 12 -0012-04 Magnolia essential oil of BALB / c mice through experimental study - sensitive airway inflammation Yang Jinhua, Li Yin Chao (1. First Affiliated Hospital of Traditional Chinese Medicine, Zhengzhou 450000; 2. Zhengzhou University College of Pharmacy Zhengzhou 450052, China) Abstract Objective: To investigate the essential oil of Magnolia BALB / e mice with allergic airway inflammation. Methods: The ovalbumin (OVA) sensitized with Freund's adjuvant induced BALB / c mice with asthma, their view of Cha Xinyi oil bronchoalveolar lavage fluid (BALF),[link widoczny dla zalogowanych], white blood cell (WBC) count of the number and classification,[link widoczny dla zalogowanych], protein content, lung pathological changes of mucosal infiltration of the bronchioles and lung eosinophils (Eos) of the number. Results: Magnolia essential oils can significantly reduce the BALI ~ 'in the Eos number (P <0.05), protein content of lung tissue Eos (P <0.05) and other inflammatory cell infiltration, and the dose-effect relationship to the role of high-dose compared with Magnolia Oil strong. Conclusion: The Magnolia oil control effect of allergic asthma, possibly by inhibiting the inflammatory infiltration of lung tissue Eos achieved. Keywords: Magnolia oil / pharmacodynamics airway inflammation / drug effects in bronchoalveolar lavage fluid / pharmacodynamics in the ring eosinophils Key words: R562.25 literature flag code: B to the terms of the pathogenesis of bronchial asthma There are two successive phase of pathological response, the early asthmatic reaction (earlyasth.maticreaction, EAR) and late phase reaction (1ateasthmaticre-action, LAR) 1-2], EAR mainly by the degranulation of airway mast cells mediated by guide, LAR mainly by the infiltration of airway inflammatory Eos mediated. I pre-sensitized and challenged with OVA produced in asthmatic guinea pig asthma model characterized by EAR, initially confirmed Magnolia essential oil has a more significant role in inflammation control EAR. On the basis of this study further observed Magnolia essential oils to airway inflammation characterized by LAR BALB / c mouse model of airway inflammation in asthmatic effects, are reported below. 1 Materials and methods 1.1 Animal Health BALB / c mice of clean grade, 50 body mass (20 ± 2) g, male and female, by the Experimental Animal Center of Henan Province, animal production license number: SCXK ( Yu) 2005-0001. 1.2 Drugs and try Jing Magnolia essential oil from Hualong Lily Magnolia Development Co., Ltd. of Henan Province Nanzhao provided sealed brown bottle, 4 ℃ refrigerator, When you use the 0.5% Tween. 80 Magnolia preparation of oil 18L per ml of liquid,
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