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Dołączył: 21 Lut 2011
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Wysłany: Sob 5:57, 26 Mar 2011 Temat postu: Christian Louboutin Ireland vre pup dfnw uyh |
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Human embryonic lung occurred light and electron microscopy
remitsshow: Accordingtothestructuralchanges ~, yithtime, thedevelopmentoflungcanbedividedintoglandularstage, canalficulargtage. andprimitiveslv ~ olarstagerespectively. Thereisflkindofundifferentiatedcellsintheepitheliumoftheconductingportion, termi-nalbudsandprimitivealveoli. thesecellsareuauallycolumnarandclaboida1. Theireyto. 01asmhasrichycogen ~ mnleB,[link widoczny dla zalogowanych], butscantyorganeUus. Inducedbythesrroundingraesanchymeve ~ els, theur ~ liffeeen-tiatedcellscanchangeintovariouskindsofepithelialcellsintheconductingandres01ratoryportions. Keywords: histogenesis; Ultrastrtctuee; blood-airbarrier; lung; hurflan, fetus (Editor Pan Xiaoling) the development of mathematical models of drug kinetics group LIU pharmacokinetics after nearly 50 years of development and become an independent field of medicine the importance of Discipline in guiding the clinical use of drugs and medicines. Dosage Form has played an increasingly important role. Pharmacokinetics of the classic is a With the development of science and technology, it is recognized that the limitations compartment model theory to more accurately from the mathematically derived quantitative drug in the body disposition status of law has become an important pharmacokinetic back problems. This article describes a little Holland pharmacokinetic studies in recent years, some of the new model theory of a physiological pharmacokinetic model of this model is to solve the classic pulp compartment model does not reflect the physiological or pathological body functions to change this lack of initiative. Dichotoma compartment model cell structure remains, but the ten compartments each have a real physiological significance, between the rooms flow together into a system with pits, the drug concentration in the chamber to accurately reflect changes in the corresponding organs tissue drug concentration by the time,[link widoczny dla zalogowanych], body function caused by physiological or pathological changes in pharmacy through the relevant parameter estimates. But because there are a large number of human physiological data is unknown,[link widoczny dla zalogowanych], physiological pharmacokinetics in animals for only a limited test. Second, the stochastic dynamic model of drug use of this model is the random process of probability theory and mathematical tools to investigate the status of drug in the body configuration, which is based on the drug enters the body as a large number of random particles, the rate constant as a construction operation R values in a range of domestic variables made with peaches. Weibull distribution of the random model focuses on the permanent retention of drug molecules within the distribution function of time, this distribution as a drug molecule enters the body by metabolism or excretion take along their addition to the time interval between the implementation. Rate constant for the dynamic model of a random variable drugs, the drugs in the human body's metabolic rate constants and concentration as the beginning of tough new moon ski rate has distributed random variable to deal with. Prayer Room type investigated by the randomness of the body of this concentration. To provide information for clinical medication. Random process model for the pharmacokinetics of the drug into the body as composed of countless particles, each particle will exercise room which is random, which briefly with random process theory of drug particles in the body dynamics. The current theoretical research is still in the initial stage. Third, non-moment analysis of drugs spider room molding moment dynamics method is a completely independent chamber model. Use of blood concentration of the first moment and zero-order moment of the business,[link widoczny dla zalogowanych], calculate the average of drug residence time in the body,[link widoczny dla zalogowanych], the other can be calculated using statistical moment concept of drug bioavailability, clearance rate, half-life and performance of the kinetic parameters such as volume of distribution. Application of moment analysis method can be estimated Ⅱ service or absorption time after intramuscular injection. In addition, the Human {Ding hour pharmacokinetics of the overall pharmacokinetics, the pharmacokinetics of multiple peaks and the model machine has begun to expel radio discussion. Ming-field force Asthma fraud robbed Joi Wong Chuk
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