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Dołączył: 21 Lut 2011
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 Wysłany: Czw 18:23, 24 Mar 2011 Temat postu: Christian Louboutin Ireland vcq zpk vnen hpe |
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To take metronidazole 1 case of polyneuropathy
Yun I, - a Yanbian Brain Hospital Neurology Department of Neurology Keywords metronidazole f l CLC R7414 {Chinese Law poisoning polyneuropathy caused by a variety of reasons, furan drugs, such as caused by chronic alcoholism compared polyneuropathy more common, but metronidazole VI services rarely cause polyneuropathy, l we have come down. Are as follows. Patients. Female, 63 years old, because of abdominal pain, diarrhea while taking metronidazole (day 12), 1 month after limb numbness, burning pain 3 months hospitalized. Negative history of diabetes, no history of drug use furans, admission blood pressure 18. O/12.0kPa, heart, lungs, abdomen were normal, conscious, brain revealed no abnormalities, limb muscle strength, muscle tone without exception, Masonic movement coordination, steady, accurate, negative sign legislation difficult to turn a blind eye, 10cm wrist upper limbs and lower limbs below the knee and the following temperature, pain disorders (retardation), joint position sense and vibration sense tuning fork dull, bilateral brachial Second,[link widoczny dla zalogowanych], there is three symmetrical tendon reflexes, bilateral knee, Achilles tendon reflex mild weakened, the pathological bilateral negative,[link widoczny dla zalogowanych], negative meningeal irritation, hands, feet wet, hair cool. With hormone,[link widoczny dla zalogowanych], B vitamin therapy, physical therapy with 1 month, numbness improved, burning kind of pain, sensory disturbances decreased to the level of both upper pairs of hands l / 2 below. Lower extremity leg l / 2 the following, the condition has markedly improved, and discharged. Discussion of the pathogenesis of toxic neuropathy is not clear,[link widoczny dla zalogowanych], several hypotheses have been proposed, such as anti-theory of pseudo-cholinesterase, antioxidant chemicals that the doctrine of anti-lipid synthesis,[link widoczny dla zalogowanych], vitamin Bl lack of doctrine, which is far more important axonal disease and axonal energy metabolism theory that toxic metabolites interfere with the nerve cells, the maintenance of axon formation reduce the supply of necessary material, so that the beginning of its distal axonal degeneration from Sheng. Retrograde direction to the development of the cell body, the phenomenon of performance against the dead, who sung a long axon, its terminals farther away from the cells, but also against the death Sheng prone to degeneration. Speculated that metronidazole caused by peripheral motor and sensory disorders in the mechanism and the mechanism of the coexistence of a variety of related. (Received 1998-09-10) high, the drug has few side effects, but the individual in the clinical application of nausea, vomiting, high blood pressure, pulmonary edema and other side effects should therefore observe in the application. Hypertension and heart failure with caution. This all observed cases, found no side effects. Thus, naloxone is the treatment of acute alcoholism rapid, simple, effective, reliable, and the ideal drug has few side effects of drug detoxification, it is widely in use in clinical work
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