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Dołączył: 21 Lut 2011
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 Wysłany: Śro 8:19, 16 Mar 2011 Temat postu: adidas scarpe ivt hlb oyjg wso |
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The progress of steroidal contraceptive drugs
4d, without a pregnancy. Mid-luteal phase of an oral 10m ~ / kg, 72h induced menstrual-like bleeding inside, suggesting that there may be spoonbills RU486 as a reminder once a month by only pregnant drug. This product is also the role of the cervix to soften and expand on the ridicule by> / 10w1 【who better flow of the cervix before the expansion. In the official fetal death in late pregnancy were, oral 1 200mg × 2 times / a × 2d, a high success rate, side effects, can replace the prostaglandins with 20 sides were ectopic pregnancy than oral drug is also effective outside, RU486 to method of injection or vaginal administration can meet unexpectedly breaks into clinical trials. In short, the drug is expected to be relatively satisfied with the reminder of a pregnancy by the only drug or menstrual induction Jing. onapristone (ZK98299), liloprlstone (and Los mifepristone. zK9 ~ 734) is carrying two new progesterone receptor antagonist, anti-progesterone activity and RU48S similar, but less anti-glucocorticoid effect,[link widoczny dla zalogowanych], is entering clinical trials 3 MG Lu j hydroxysteroid dehydrogenase inhibition consonants jepostahe (Win32729) to rhesus monkeys orally once a day 1O0m § × 5d, can inhibit ovarian and placental progesterone synthesis, reducing the level of progesterone in vivo, leading to vaginal bleeding. Entropy bed oral once 400mgx2 times / d × 4d, abortion successful and well tolerated. Who stabbed through 49d, oral 200mg × 4 times / dx7d, full production rate of 84 Wei, is a promising new drugs against early pregnancy. If and prostaglandin E and use, amenorrhea 56d mouth per day crisp 60Otag (early 200mg,[link widoczny dla zalogowanych], late 400mg) × 5d, d4 placed lOmgPGE: Yindao Long (2h1 times × 3 times), all successful abortion. In recent years, including the anti-progesterone receptor shot a new steroidal anti-progesterone mlfep / 'istone (mifepristone, RU486, the conclusion RU33486) ~ Education glimpse of drug research in a major breakthrough. The drug is not progesterone, androgen, estrogen, or the current steroidal anti-estrogen contraceptives,[link widoczny dla zalogowanych], improvements and new drugs are still the old 4 my head wrapped in a variety of long-term development of progesterone injection Tuo Qi-depth development of both drug development. Mainly through the improvement of old drug pharmaceutics research to develop new formulations, the earlier focus on the D-A norethindrone, norethindrone recent years is on, vinegar, etc. norethisterone more reports; Not only that, oral dual photo, three other new photos formulation is also extended to some new contraceptives, such as desogestrel, gestodene, etc. It is worth noting that the new trend. As these new contraceptives no androgenic activity, without affecting the HDL is not D-acetylene promise of progesterone and other old drugs side effects, so clinical safer, is very promising. New drug development,[link widoczny dla zalogowanych], the more important new drugs in recent years, pregnant ene to remove the oxygen, acetylene Connaught proxetil,[link widoczny dla zalogowanych], but mainly the advent of gestodene, which is by far the smallest Shuo a dose oral contraceptives, they will replace the current clinical alkyne D-quinolone and acetylene promise progesterone, should be given attention. Lou is another anti-progesterone hormone drug, with the exception of a hydroxysteroid dehydrogenase inhibitor 3 epostane, the main twist is a progesterone receptor antagonist Ru486, etc., clinical tips are good prospects. In particular, these new drugs and prostaglandins associated units to use, anti-early pregnancy can greatly improve the whole flow rate, the future will be a new direction for anti-fertility drugs, and maturity in clinical practice. China should see this trend, strengthening organizational leadership and scientific management to accelerate development of new drugs t on the one hand, such as RU486, eposta ~ e and desogestrel, Connaught oxime propargyl esters, ketones and other torch pregnant J on the other hand two more pharmaceutics research can not be ignored, Huan 5RU486 granted by the same drought closed the base glistening rate of pregnant photos to fill the two-, three photos, and other implanted Jing blank, the old drug is more to do perfect, continue to provide effective measures for family planning, so that steroidal anti-fertility drugs in controlling population growth play a greater role. t Pharmaceutical University, 1991 Subscription 'Pharmaceutical Journal' organized by the China Pharmaceutical Association, domestic and international public offering. Jun benzene within the cellar including pharmacology, natural medicine, chemistry, synthetic chemistry, drug analysis of pharmacy, pharmacognosy and research papers and other aspects of antibiotics research chu presentations, academic trends, review and Commentary and so on. The Journal is monthly, each 8o pages, price 3.50 yuan each, the domestic readers go to the local post office subscriptions, remittances can be sent directly to the editorial department, code 2-233 domestic journals, foreign readers to please China Book Trading Corporation (China International Publishing, Box 399, Beijing) subscriptions, foreign periodicals code, M] 05 magazine still] 979 years of the existence of more than a few copies may purchase directly sensitive to the editorial board mail order. Editorial Office: Beijing Xian Nong Tan Street, 1 0
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